What class of drug is tipranavir?

What class of drug is tipranavir?

Tipranavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood.

What is the mechanism of action of zidovudine?

Mechanism of action AZT works by selectively inhibiting HIV’s reverse transcriptase, the enzyme that the virus uses to make a DNA copy of its RNA.

Is saquinavir a protease inhibitor?

AIDS: Saquinavir, developed by Hoffmann-LaRoche under the trade name Invirase, is the first protease inhibitor to be approved by the Food and Drug Administration (FDA) for use in combination with one or more unspecified nucleoside analogs.

Who makes Norvir?

Ritonavir is manufactured as Norvir by AbbVie, Inc.. The US Food and Drug Administration (FDA) approved ritonavir on March 1, 1996, making it the seventh U.S.-approved antiretroviral drug and the second U.S.-approved protease inhibitor (after saquinavir four months earlier).

Is tipranavir a protease inhibitor?

Tipranavir (TPV) is the first of a new class of non-peptidic protease inhibitors (NPPIs). It is a sulphonamide-containing dihydropyrone, which is highly selective for the HIV protease enzyme and demonstrates potent in vitro activity against wild-type HIV-1 and HIV-2.

What is the medicine carbamazepine used for?

Carbamazepine is used to treat certain types of seizures (epilepsy). It is also used to relieve pain due to trigeminal neuralgia (tic douloureux) and in the treatment of bipolar disorder (manic-depressive illness). Carbamazepine works in the brain and nervous system to control seizures, pain, and bipolar disorder.

Is ritonavir an enzyme inducer or inhibitor?

Data synthesis: Ritonavir is a well-known inhibitor of the metabolism of numerous medications that are substrates of the CYP3A and CYP2D6 pathways. It also exhibits a biphasic, time-dependent effect on P-glycoprotein of inhibition followed by induction.

How is zidovudine administered?

Administration. RETROVIR IV (zidovudine injection) Infusion is administered intravenously at a constant rate over 1 hour. Rapid infusion or bolus injection should be avoided.

What type of inhibitor is saquinavir?

Saquinavir is an HIV-1 protease inhibitor used in combination with ritonavir and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection.

What is the generic name for Norvir?

Ritonavir (Norvir) is a protease inhibitor and a booster medication. At high doses it stops the HIV virus from making copies of itself, and at low doses it raises the levels of other HIV ARVs.

Who invented ritonavir?

Dr Dale Kempf has nearly 35 years of pharmaceutical R&D experience, mostly in antiviral and infectious diseases research. He is a co-inventor of Norvir™ (ritonavir) and Kaletra™ (lopinavir/ritonavir), HIV protease inhibitors that are widely used for the therapy of HIV infection.

Why is carbamazepine hazardous?

Carbamazepine may cause life-threatening allergic reactions called Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). These allergic reactions may cause severe damage to the skin and internal organs.