What does CCL3 stand for?
Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the CCL gene.
What are the Football League play-off semi-finals?
The play-off semi-finals were also played over two legs and were contested by the teams who finished in 3rd, 4th, 5th and 6th place in the Football League Second Division, the 4th, 5th, 6th and 7th placed teams in the Football League Third Division and the 3rd, 4th, 5th and 6th place teams in the Football League Fourth Division table.
What is the mechanism of action of ccccl3?
CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5.
Who won the FA Cup in 1992?
The 1992–93 Football League Cup (known as the Coca-Cola Cup for sponsorship reasons) was the 33rd Football League Cup, a knockout competition for England’s top 92 football clubs. The competition name reflects a sponsorship deal with soft drink brand Coca-Cola . Arsenal won the competition, beating Sheffield Wednesday 2–1 in the final .
CCL3 C-C motif chemokine ligand 3 [ (human)] Gene ID: 6348, updated on 12-May-2019. This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5.
What is the role of CCL3 in memory T cells?
Previously, we and others have demonstrated that CCL3 plays an essential role in orchestrating T cell—antigen-presenting cell (APC) encounters in the draining LN following vaccination, and such interactions enhance the magnitude of the memory T cell pool ( 3 – 5 ).
What triggers CCL3 and CCl4 expression?
Bacterial toxins, viral infections, TNFα, IFN-γ, IL-1β, and IL-6 are some of the stimuli that induce the expression of CCL3 and/or CCL4 in vitro from multiple cell types including monocytes/macrophages, DCs, and epithelial cells.
What is the role of CCL3 in the early phase of immune priming?
During this early phase of immune priming, NK cells constitute the major producers of IFNγ in the TDLN. CCL3 also enhances CD8+ T cell proliferation and differentiation by augmenting DC capacity to drive T cell activation in the TDLN.