What is dinitro used for?
The most commercially important dinitrocresol, 4,6-dinitro-o-cresol (DNOC), is a yellow solid with no smell. It is used primarily for insect control and crop protection. It may be sold under several trade names, including Antinonnin, Detal, and Dinitrol.
What is dinitro O cresol used for?
4,6-dinitro-o-cresol is a hydroxytoluene that is o-cresol carrying nitro substituents at positions 4 and 6. It has a role as a dinitrophenol insecticide, a fungicide and a herbicide. It is a dinitrophenol acaricide, a nitrotoluene and a hydroxytoluene. It derives from an o-cresol and a 2,4-dinitrophenol.
Is Dinitrocresol an Uncoupler?
It is concluded that DNOC is a potent potent protonophore acting as a classical uncoupler of oxidative phosphorylation in rat liver mitochondria by dissipating the proton electrochemical gradient.
What is the chemical name of Chlorocresol?
p-Chlorocresol is the organic compound with the formula ClC6H4OH. It is a monochlorinated m-cresol….p-Chlorocresol.
|Preferred IUPAC name 4-Chloro-3-methylphenol|
|Other names p-chloro-m-cresol; PCMC; Preventol; CMK|
What do you mean by uncoupler?
An uncoupler or uncoupling agent is a molecule that disrupts oxidative phosphorylation in prokaryotes and mitochondria or photophosphorylation in chloroplasts and cyanobacteria by dissociating the reactions of ATP synthesis from the electron transport chain.
Is aspirin an uncoupler?
Aspirin has been shown to have three additional modes of action. It uncouples oxidative phosphorylation in cartilaginous (and hepatic) mitochondria, by diffusing from the intermembrane space as a proton carrier back into the mitochondrial matrix, where it ionizes once again to release protons.
What is Chlorocresol made from?
p-Chlorocresol is the organic compound with the formula ClC6H4OH. It is a monochlorinated m-cresol. It is a white or colorless solid that is only slightly soluble in water. p-Chlorocresol is prepared by chlorination of m-cresol.
What is use of Chlorocresol?
Chlorocresol is used to prevent infections. How Chlorocresol works. Chlorocresol has disinfectant, antiseptic and bactericidal properties. It kills bacteria, and prevents microbial growth. It is also used in various pharmaceutical products to increase shelf life.
Is aspirin an Uncoupler?
What is the function of Uncouplers?
Uncoupling proteins are mitochondrial carrier proteins which are able to dissipate the proton gradient of the inner mitochondrial membrane. This uncoupling process reduces the amount of ATP generated through an oxidation of fuels.
How does aspirin act as an uncoupler?
Other methods of action Aspirin has been shown to have three additional modes of action. It uncouples oxidative phosphorylation in cartilaginous (and hepatic) mitochondria, by diffusing from the intermembrane space as a proton carrier back into the mitochondrial matrix, where it ionizes once again to release protons.
Why is aspirin irreversible?
(2) However, the biochemical mechanism of aspirin’s therapeutic action is unique: aspirin covalently modifies the COX-2 enzyme through acetylation of Ser530 near its active site, which prevents proper binding of the native substrate and thus leads to its irreversible inhibition.