What is VZV PCR?

What is VZV PCR?

The DiaSorin Simplexa™ Varicella Zoster Virus (VZV) Direct FDA approved assay is a rapid real-time PCR that enables the direct amplification, detection of VZV from both cutaneous and mucocutaneous swab specimens and CSF specimens.

What does VZV positive mean?

Positive results indicate the presence of detectable VZV IgG antibodies. A positive result generally indicates exposure to the pathogen or administration of specific immunoglobulins, but it is no indication of active infection or stage of disease.

What is the normal range for varicella zoster virus?

Reference Range(s)

Index Interpretation
<135.00 Negative – Antibody not detected
135.00-164.99 Equivocal
≥165.00 Positive – Antibody detected

What is a VZV test?

Varicella zoster virus tests detect either antibodies produced by the immune system in response to a VZV infection or detect the virus itself. Tests for chickenpox and shingles may be performed to detect and diagnose a current or past infection with VZV.

How do you swab for VZV?

Swabs must be placed individually into separate, empty tubes to avoid contamination. Place swabs directly into tubes. Do not place transport medium into the tube; the specimen MUST be kept dry. Tubes must be individually labeled and must be resistant to breakage.

How long does a VZV PCR take?

Turnaround time for PCR results is typically 2 business days after receipt of specimen(s).

What is VZV IgG antibody?

A positive IgG ELISA result indicates that a person has antibodies to VZV either from past varicella disease or vaccination. This test cannot distinguish whether the antibodies were from a past episode of varicella or vaccination.

What is normal varicella zoster IgG?

165.0 IV or greater: Positive – IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. 0.90 ISR or less: Negative – No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal – Repeat testing in 10-14 days may be helpful.

What are VZV antibodies?

Description. Varicella Zoster Antibodies, IgG testing is useful for the determination of an individual’s immune status and/or to aid in the diagnosis of varicella zoster infection. A positive VZV IgG result indicates the presence of antibodies to varicella zoster virus.

What is PCR used for?

PCR is used to diagnose genetic disease and to detect low levels of viral infection. In forensic medicine it is used to analyze minute traces of blood and other tissues in order to identify the donor by his genetic “fingerprint.”

What is a PCR procedure?

PCR is an essential technique in cloning procedure which allows generation of large amounts of pure DNA from tiny amount of template strand and further study of a particular gene. The Human Genome Project (HGP) for determining the sequence of the 3 billion base pairs in the human genome, relied heavily on PCR.

What is PCR lab testing?

The PCR test forms the basis of a number of tests that can answer many different medical questions that help physicians diagnose and treat patients. For example, PCR tests can detect and identify pathogenic organisms in patients, especially those that are difficult to cultivate (for example, HIV and other viruses and certain fungi).

What is a viral PCR Panel?

Respiratory Viral Panel PCR (RVPP) and Film Array Viral Panel PCR (FARVPP) The Respiratory Viral Panel PCR (RVPP, said like R vap) and Film Array Viral Panel PCR (FARVPP, said like FAR vap) are tests that help your child’s doctor to identify different viruses and bacteria. One of these two tests will be chosen based on your child’s doctor’s…