Which is O glycoside?
When a monosaccharide (or sugar fragment of any size) is condensed with either an aliphatic or aromatic alcohol, or another sugar moiety through an oxygen, a glycoside bond is formed. General examples of O-glycosides are shown in Figure 2.1.
What are glycosides used for?
Cardiac glycosides are medicines for treating heart failure and certain irregular heartbeats. They are one of several classes of drugs used to treat the heart and related conditions. These drugs are a common cause of poisoning.
What is glycosides and examples?
: any of numerous sugar derivatives that contain a nonsugar group bonded to an oxygen or nitrogen atom and that on hydrolysis yield a sugar (such as glucose) Other Words from glycoside Example Sentences Learn More About glycoside.
Are glycosides harmful?
All parts of the plant containing cardiac glycosides are toxic, with the roots and seeds typically containing the highest percentage of toxins. Ingestion of 5-15 N. oleander leaves has resulted in a fatal poisoning.
Where are glycosides found?
Many glycosides occur in plants, often as flower and fruit pigments; for example, anthocyanins. Various medicines, condiments, and dyes from plants occur as glycosides; of great value are the heart-stimulating glycosides of Digitalis and Strophanthus, members of a group known as cardiac glycosides.
How glycoside is formed?
Glycosides are formed when the anomeric (hemiac-etal or hemiketal) hydroxyl group of a monosaccharide undergoes condensation with the hydroxyl group of a second molecule, with the elimination of water.
What are side effects of cardiac glycosides?
The most common side effects include dizziness, fatigue, headache, anxiety, gastrointestinal upset, change in taste and blurred vision. Severe side effects include seizures and coma, heart block, atrial and ventricular arrhythmias and sudden cardiac death.
What are C glycosides?
According to Levy and Tang the term C-glycoside describes those structures in which a common structural motifs the presence of carbon functionality at what would otherwise be the anomeric position of a sugar or derivative. A variety of natural product C-glycosides has been described.
What medications are cardiac glycosides?
Cardiac glycosides include: Digoxin (Lanoxicaps, Lanoxin, Digibind) Digitoxin (Crystodigin)
What foods contain glycosides?
Important staple foods for some parts of the world (such as cassava and sorghum) contain cyanogenic glycosides. Other edible plants containing cyanogenic glycosides include bamboo shoot, flaxseeds, and seeds of stone fruits such as apricot and peach, seeds of peas and beans such as lima beans, and shell of soya beans.
How do glycosides form?
Is digoxin a glycoside?
Introduction. Digitalis and its derivatives such as digoxin and digitoxin are cardiac glycosides used typically in the therapy of congestive heart failure and atrial fibrillation.
What is the difference between O-glycoside and C-Gly COSIDE?
Glycosides can be linked by an O- (an O-glycoside), N- (a glycosylamine), S-(a thioglycoside), or C- (a C-glycoside) glycosidic bond. According to the IUPAC, the name “C-glycoside” is a misnomer; the preferred term is “C-glycosyl compound”.
What are glycosides used for in medicine?
Many such plant glycosides are used as medications. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body.A glycoside is a molecule consisting of a sugar and a non-sugar group, called an aglycone.
What is the difference between glycoside and poison?
In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body.A glycoside is a molecule consisting of a sugar and a non-sugar group, called an aglycone. The sugar group is known as the glycone and can consist of a single sugar group or several sugar groups.
What is iridoid glycoside?
Figure 11. Iridoid glycosides. Iridoids are ecologically very interesting, because several insect herbivores from different families specialized in feeding on iridoid glycoside-containing plants sequester iridoid glycosides in higher concentrations.